Toxic Effect of Silica Nanoparticles on Endothelial Cells through DNA Damage Response via Chk1-Dependent G2/M Checkpoint

Silica nanoparticles have become promising carriers for drug delivery or gene therapy. Endothelial cells could be directly exposed to silica nanoparticles by intravenous administration. However, the underlying toxic effect mechanisms of silica nanoparticles on endothelial cells are still poorly unde...

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Detalles Bibliográficos
Autores principales: Duan, Junchao, Yu, Yongbo, Li, Yang, Yu, Yang, Li, Yanbo, Zhou, Xianqing, Huang, Peili, Sun, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631220/
https://www.ncbi.nlm.nih.gov/pubmed/23620807
http://dx.doi.org/10.1371/journal.pone.0062087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631220/
https://www.ncbi.nlm.nih.gov/pubmed/23620807
http://dx.doi.org/10.1371/journal.pone.0062087

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