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Sensing and alarm function of resident memory CD8(+) T cells

CD8(+) T cells eliminate intracellular infections through two contact-dependent effector functions: cytolysis and antiviral cytokine secretion. Here, we identify an additional function for memory CD8(+) T cells persisting at frontline sites of microbial exposure: as local sensors of previously encou...

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Detalles Bibliográficos
Autores principales: Schenkel, Jason M., Fraser, Kathryn A., Vezys, Vaiva, Masopust, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631432/
https://www.ncbi.nlm.nih.gov/pubmed/23542740
http://dx.doi.org/10.1038/ni.2568