Cargando…
Sensing and alarm function of resident memory CD8(+) T cells
CD8(+) T cells eliminate intracellular infections through two contact-dependent effector functions: cytolysis and antiviral cytokine secretion. Here, we identify an additional function for memory CD8(+) T cells persisting at frontline sites of microbial exposure: as local sensors of previously encou...
Autores principales: | Schenkel, Jason M., Fraser, Kathryn A., Vezys, Vaiva, Masopust, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631432/ https://www.ncbi.nlm.nih.gov/pubmed/23542740 http://dx.doi.org/10.1038/ni.2568 |
Ejemplares similares
-
CD4(+) resident memory T cells dominate immunosurveillance and orchestrate local recall responses
por: Beura, Lalit K., et al.
Publicado: (2019) -
Robust Iterative Stimulation with Self-Antigens Overcomes CD8(+) T Cell Tolerance to Self- and Tumor Antigens
por: Nelson, Christine E., et al.
Publicado: (2019) -
Depleting CD103(+) resident memory T cells in vivo reveals immunostimulatory functions in oral mucosa
por: Stolley, J. Michael, et al.
Publicado: (2023) -
Dynamic T cell migration program provides resident memory within intestinal epithelium
por: Masopust, David, et al.
Publicado: (2010) -
The precursors of CD8(+) tissue resident memory T cells: from lymphoid organs to infected tissues
por: Kok, Lianne, et al.
Publicado: (2021)