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Stress-dependent dilated cardiomyopathy in mice with cardiomyocyte-restricted inactivation of cyclic GMP-dependent protein kinase I

AIMS: Cardiac hypertrophy is a common and often lethal complication of arterial hypertension. Elevation of myocyte cyclic GMP levels by local actions of endogenous atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) or by pharmacological inhibition of phosphodiesterase-5 was shown...

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Detalles Bibliográficos
Autores principales: Frantz, Stefan, Klaiber, Michael, Baba, Hideo A., Oberwinkler, Heike, Völker, Katharina, Gaβner, Birgit, Bayer, Barbara, Abeβer, Marco, Schuh, Kai, Feil, Robert, Hofmann, Franz, Kuhn, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631523/
https://www.ncbi.nlm.nih.gov/pubmed/22199120
http://dx.doi.org/10.1093/eurheartj/ehr445