The mannose 6-phosphate-binding sites of M6P/IGF2R determine its capacity to suppress matrix invasion by squamous cell carcinoma cells

The M6P (mannose 6-phosphate)/IGF2R (insulin-like growth factor II receptor) interacts with a variety of factors that impinge on tumour invasion and metastasis. It has been shown that expression of wild-type M6P/IGF2R reduces the tumorigenic and invasive properties of receptor-deficient SCC-VII squa...

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Detalles Bibliográficos
Autores principales: Probst, Olivia C., Karayel, Evren, Schida, Nicole, Nimmerfall, Elisabeth, Hehenberger, Elisabeth, Puxbaum, Verena, Mach, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632087/
https://www.ncbi.nlm.nih.gov/pubmed/23347038
http://dx.doi.org/10.1042/BJ20121422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632087/
https://www.ncbi.nlm.nih.gov/pubmed/23347038
http://dx.doi.org/10.1042/BJ20121422

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