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The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover
The androgen receptor (AR) is a key molecule involved in prostate cancer (PC) development and progression. Post-translational modification of the AR by co-regulator proteins can modulate its transcriptional activity. To identify which demethylases might be involved in AR regulation, an siRNA screen...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632104/ https://www.ncbi.nlm.nih.gov/pubmed/23435229 http://dx.doi.org/10.1093/nar/gkt106 |