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Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome

A key signature of module exchange in the genome is phase symmetry of exons, suggestive of exon shuffling events that occurred without disrupting translation reading frame. At the protein level, intrinsic structural disorder may be another key element because disordered regions often serve as functi...

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Detalles Bibliográficos
Autores principales: Schad, Eva, Kalmar, Lajos, Tompa, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632108/
https://www.ncbi.nlm.nih.gov/pubmed/23460204
http://dx.doi.org/10.1093/nar/gkt110