Cargando…
Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome
A key signature of module exchange in the genome is phase symmetry of exons, suggestive of exon shuffling events that occurred without disrupting translation reading frame. At the protein level, intrinsic structural disorder may be another key element because disordered regions often serve as functi...
Autores principales: | Schad, Eva, Kalmar, Lajos, Tompa, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632108/ https://www.ncbi.nlm.nih.gov/pubmed/23460204 http://dx.doi.org/10.1093/nar/gkt110 |
Ejemplares similares
-
Verification of alternative splicing variants based on domain integrity, truncation length and intrinsic protein disorder
por: Hegyi, Hedi, et al.
Publicado: (2011) -
Cellular Chaperone Function of Intrinsically Disordered Dehydrin ERD14
por: Murvai, Nikoletta, et al.
Publicado: (2021) -
Intrinsically Disordered Linkers Impart Processivity on Enzymes by Spatial Confinement of Binding Domains
por: Szabo, Beata, et al.
Publicado: (2019) -
Intrinsic protein disorder uncouples affinity from binding specificity
por: Lázár, Tamas, et al.
Publicado: (2022) -
Reply to “Intrinsic protein disorder uncouples affinity from binding specificity”
por: Lázár, Tamás, et al.
Publicado: (2023)