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Two-step model of stop codon recognition by eukaryotic release factor eRF1

Release factor eRF1 plays a key role in the termination of protein synthesis in eukaryotes. The eRF1 consists of three domains (N, M and C) that perform unique roles in termination. Previous studies of eRF1 point mutants and standard/variant code eRF1 chimeras unequivocally demonstrated a direct inv...

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Detalles Bibliográficos
Autores principales: Kryuchkova, Polina, Grishin, Alexander, Eliseev, Boris, Karyagina, Anna, Frolova, Ludmila, Alkalaeva, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632111/
https://www.ncbi.nlm.nih.gov/pubmed/23435318
http://dx.doi.org/10.1093/nar/gkt113