Cargando…

Two-step model of stop codon recognition by eukaryotic release factor eRF1

Release factor eRF1 plays a key role in the termination of protein synthesis in eukaryotes. The eRF1 consists of three domains (N, M and C) that perform unique roles in termination. Previous studies of eRF1 point mutants and standard/variant code eRF1 chimeras unequivocally demonstrated a direct inv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kryuchkova, Polina, Grishin, Alexander, Eliseev, Boris, Karyagina, Anna, Frolova, Ludmila, Alkalaeva, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632111/ https://www.ncbi.nlm.nih.gov/pubmed/23435318 http://dx.doi.org/10.1093/nar/gkt113

Ejemplares similares

A single amino acid change of translation termination factor eRF1 switches between bipotent and omnipotent stop-codon specificity(†)
por: Eliseev, Boris, et al.
Publicado: (2011)

Adenine and guanine recognition of stop codon is mediated by different N domain conformations of translation termination factor eRF1
por: Bulygin, Konstantin N., et al.
Publicado: (2011)

PABP enhances release factor recruitment and stop codon recognition during translation termination
por: Ivanov, Alexandr, et al.
Publicado: (2016)

Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1
por: Wong, Leo E., et al.
Publicado: (2012)

New insights into stop codon recognition by eRF1
por: Blanchet, Sandra, et al.
Publicado: (2015)

Genetic analysis of L123 of the tRNA-mimicking eukaryote release factor eRF1, an amino acid residue critical for discrimination of stop codons
por: Saito, Kazuki, et al.
Publicado: (2015)

GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding
por: Kononenko, Artem V., et al.
Publicado: (2010)

Termination of translation in eukaryotes is mediated by the quaternary eRF1•eRF3•GTP•Mg(2+) complex. The biological roles of eRF3 and prokaryotic RF3 are profoundly distinct
por: Mitkevich, Vladimir A., et al.
Publicado: (2006)

Structural characterization of eRF1 mutants indicate a complex mechanism of stop codon recognition
por: Pillay, Shubhadra, et al.
Publicado: (2016)

NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor
por: Mantsyzov, Alexey B, et al.
Publicado: (2010)

eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons
por: Yang, Qian, et al.
Publicado: (2019)

Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing eRF1-eRF3 or eRF1-ABCE1
por: Preis, Anne, et al.
Publicado: (2014)

Invariant amino acids essential for decoding function of polypeptide release factor eRF1
por: Kolosov, Petr, et al.
Publicado: (2005)

A genetic approach for analyzing the co-operative function of the tRNA mimicry complex, eRF1/eRF3, in translation termination on the ribosome
por: Wada, Miki, et al.
Publicado: (2014)

Mutation at Tyrosine in AMLRY (GILRY Like) Motif of Yeast eRF1 on Nonsense Codons Suppression and Binding Affinity to eRF3
por: Akhmaloka,, et al.
Publicado: (2008)

Recognition of 3′ nucleotide context and stop codon readthrough are determined during mRNA translation elongation
por: Biziaev, Nikita, et al.
Publicado: (2022)

Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1
por: Feng, Tianshu, et al.
Publicado: (2014)

Misdecoding of rare CGA codon by translation termination factors, eRF1/eRF3, suggests novel class of ribosome rescue pathway in S. cerevisiae
por: Wada, Miki, et al.
Publicado: (2018)

Effect of small molecule eRF3 degraders on premature termination codon readthrough
por: Baradaran-Heravi, Alireza, et al.
Publicado: (2021)

Decoding accuracy in eRF1 mutants and its correlation with pleiotropic quantitative traits in yeast
por: Merritt, Gloria H., et al.
Publicado: (2010)

Translational read-through promotes aggregation and shapes stop codon identity
por: Kramarski, Lior, et al.
Publicado: (2020)

Thermodynamic and Kinetic Insights into Stop Codon Recognition by Release Factor 1
por: Trappl, Krista, et al.
Publicado: (2014)

Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3
por: Beißel, Christian, et al.
Publicado: (2019)

N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination
por: Urakov, Valery N, et al.
Publicado: (2006)

Translation initiation factor eIF3 promotes programmed stop codon readthrough
por: Beznosková, Petra, et al.
Publicado: (2015)

Partitioning between recoding and termination at a stop codon–selenocysteine insertion sequence
por: Kotini, Suresh Babu, et al.
Publicado: (2015)

Principles of start codon recognition in eukaryotic translation initiation
por: Lind, Christoffer, et al.
Publicado: (2016)

Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP
por: des Georges, Amédée, et al.
Publicado: (2014)

Translational fidelity maintenance preventing Ser mis-incorporation at Thr codon in protein from eukaryote
por: Zhou, Xiao-Long, et al.
Publicado: (2013)

Selection for tandem stop codons in ciliate species with reassigned stop codons
por: Fleming, Ira, et al.
Publicado: (2019)

Studies on human eRF3-PABP interaction reveal the influence of eRF3a N-terminal glycin repeat on eRF3-PABP binding affinity and the lower affinity of eRF3a 12-GGC allele involved in cancer susceptibility
por: Jerbi, Soumaya, et al.
Publicado: (2016)

Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough
por: Lee, Rhianna E., et al.
Publicado: (2022)

Elongation factor eEF1B modulates functions of the release factors eRF1 and eRF3 and the efficiency of translation termination in yeast
por: Valouev, Igor A, et al.
Publicado: (2009)

Molecular Basis of eRF3 Recognition by the MLLE Domain of Poly(A)-Binding Protein
por: Kozlov, Guennadi, et al.
Publicado: (2010)

In eubacteria, unlike eukaryotes, there is no evidence for selection favouring fail-safe 3’ additional stop codons
por: Ho, Alexander T., et al.
Publicado: (2019)

Human mitochondria require mtRF1 for translation termination at non-canonical stop codons
por: Krüger, Annika, et al.
Publicado: (2023)

Increased expression of tryptophan and tyrosine tRNAs elevates stop codon readthrough of reporter systems in human cell lines
por: Beznosková, Petra, et al.
Publicado: (2021)

uS3/Rps3 controls fidelity of translation termination and programmed stop codon readthrough in co-operation with eIF3
por: Poncová, Kristýna, et al.
Publicado: (2019)

Monitoring translation in all reading frames downstream of weak stop codons provides mechanistic insights into the impact of nucleotide and cellular contexts
por: Loughran, Gary, et al.
Publicado: (2022)

In Aspergillus nidulans the Suppressors suaA and suaC Code for Release Factors eRF1 and eRF3 and suaD Codes for a Glutamine tRNA
por: Liu, Wen, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2kvi3i1dr56bs572uvon1c950n