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The σ(70) region 1.2 regulates promoter escape by unwinding DNA downstream of the transcription start site
The mechanisms of abortive synthesis and promoter escape during initiation of transcription are poorly understood. Here, we show that, after initiation of RNA synthesis, non-specific interaction of σ(70) region 1.2, present in all σ(70) family factors, with the non-template strand around position −4...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632114/ https://www.ncbi.nlm.nih.gov/pubmed/23430153 http://dx.doi.org/10.1093/nar/gkt116 |