A far-upstream (−70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration

SOX9 encodes a transcription factor that presides over the specification and differentiation of numerous progenitor and differentiated cell types, and although SOX9 haploinsufficiency and overexpression cause severe diseases in humans, including campomelic dysplasia, sex reversal and cancer, the mec...

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Detalles Bibliográficos
Autores principales: Mead, Timothy J., Wang, Qiuqing, Bhattaram, Pallavi, Dy, Peter, Afelik, Solomon, Jensen, Jan, Lefebvre, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632127/
https://www.ncbi.nlm.nih.gov/pubmed/23449223
http://dx.doi.org/10.1093/nar/gkt140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632127/
https://www.ncbi.nlm.nih.gov/pubmed/23449223
http://dx.doi.org/10.1093/nar/gkt140

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