A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis

Cellular genomes are constantly damaged by endogenous and exogenous agents that covalently and structurally modify DNA to produce DNA lesions. Although most lesions are mended by various DNA repair pathways in vivo, a significant number of damage sites persist during genomic replication. Our underst...

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Detalles Bibliográficos
Autores principales: Taggart, David J., Camerlengo, Terry L., Harrison, Jason K., Sherrer, Shanen M., Kshetry, Ajay K., Taylor, John-Stephen, Huang, Kun, Suo, Zucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632128/
https://www.ncbi.nlm.nih.gov/pubmed/23470999
http://dx.doi.org/10.1093/nar/gkt141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632128/
https://www.ncbi.nlm.nih.gov/pubmed/23470999
http://dx.doi.org/10.1093/nar/gkt141

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