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Short-Term In-Vitro Expansion Improves Monitoring and Allows Affordable Generation of Virus-Specific T-Cells against Several Viruses for a Broad Clinical Application

Adenoviral infections are a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric patients. Adoptive transfer of donor-derived human adenovirus (HAdV)-specific T-cells represents a promising treatment option. However, the difficulty in id...

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Detalles Bibliográficos
Autores principales: Geyeregger, René, Freimüller, Christine, Stevanovic, Stefan, Stemberger, Julia, Mester, Gabor, Dmytrus, Jasmin, Lion, Thomas, Rammensee, Hans-Georg, Fischer, Gottfried, Eiz-Vesper, Britta, Lawitschka, Anita, Matthes, Susanne, Fritsch, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632539/
https://www.ncbi.nlm.nih.gov/pubmed/23630567
http://dx.doi.org/10.1371/journal.pone.0059592