Secondary B Cell Receptor Diversification Is Necessary for T Cell Mediated Neuro-Inflammation during Experimental Autoimmune Encephalomyelitis

BACKGROUND: Clinical studies of B cell depletion in Multiple Sclerosis (MS) have revealed that B Lymphocytes are involved in the neuro-inflammatory process, yet it remains unclear how B cells can exert pro- and anti-inflammatory functions during MS. Experimental Autoimmune Encephalomyelitis (EAE) is...

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Detalles Bibliográficos
Autores principales: Galicia, Georgina, Boulianne, Bryant, Pikor, Natalia, Martin, Alberto, Gommerman, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632548/
https://www.ncbi.nlm.nih.gov/pubmed/23613859
http://dx.doi.org/10.1371/journal.pone.0061478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632548/
https://www.ncbi.nlm.nih.gov/pubmed/23613859
http://dx.doi.org/10.1371/journal.pone.0061478

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