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The Absence of Mrp4 Has No Effect on the Recruitment of Neutrophils and Eosinophils into the Lung after LPS, Cigarette Smoke or Allergen Challenge

The multidrug resistance protein 4 (Mrp4) is an ATP-binding cassette transporter that is capable of exporting the second messenger cAMP from cells, a process that might regulate cAMP-mediated anti-inflammatory processes. However, using LPS- or cigarette smoke (CS)-inflammation models, we found that...

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Detalles Bibliográficos
Autores principales: Schymeinsky, Jürgen, Mayer, Hannah, Tomsic, Christopher, Tilp, Cornelia, Schuetz, John D., Cui, Yunhai, Wollin, Lutz, Gantner, Florian, Erb, Klaus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632556/
https://www.ncbi.nlm.nih.gov/pubmed/23613808
http://dx.doi.org/10.1371/journal.pone.0061193