Nelfinavir Inhibits Intra-Mitochondrial Calcium Influx and Protects Brain against Hypoxic-Ischemic Injury in Neonatal Mice

Nelfinavir (NLF), an antiretroviral agent, preserves mitochondrial membranes integrity and protects mature brain against ischemic injury in rodents. Our study demonstrates that in neonatal mice NLF significantly limits mitochondrial calcium influx, the event associated with protection of the brain a...

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Detalles Bibliográficos
Autores principales: Utkina-Sosunova, Irina V., Niatsetskaya, Zoya V., Sosunov, Sergey A., Ratner, Veniamin I., Matsiukevich, Dzmitry, Ten, Vadim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632564/
https://www.ncbi.nlm.nih.gov/pubmed/23614049
http://dx.doi.org/10.1371/journal.pone.0062448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632564/
https://www.ncbi.nlm.nih.gov/pubmed/23614049
http://dx.doi.org/10.1371/journal.pone.0062448

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