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Molecular Ageing of Alpha- and Beta-Synucleins: Protein Damage and Repair Mechanisms
Abnormal α-synuclein aggregates are hallmarks of a number of neurodegenerative diseases. Alpha synuclein and β-synucleins are susceptible to post-translational modification as isoaspartate protein damage, which is regulated in vivo by the action of the repair enzyme protein L-isoaspartyl O-methyltra...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632608/ https://www.ncbi.nlm.nih.gov/pubmed/23630590 http://dx.doi.org/10.1371/journal.pone.0061442 |