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A task-based approach for Gene Ontology evaluation

BACKGROUND: The Gene Ontology and its associated annotations are critical tools for interpreting lists of genes. Here, we introduce a method for evaluating the Gene Ontology annotations and structure based on the impact they have on gene set enrichment analysis, along with an example implementation....

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Detalles Bibliográficos
Autores principales: Clarke, Erik L, Loguercio, Salvatore, Good, Benjamin M, Su, Andrew I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633003/
https://www.ncbi.nlm.nih.gov/pubmed/23734599
http://dx.doi.org/10.1186/2041-1480-4-S1-S4