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How oligoclonal are germinal centers? A new method for estimating clonal diversity from immunohistological sections
BACKGROUND: The germinal center (GC) reaction leads to antibody affinity maturation and generation of memory B cells, but its underlying mechanisms are poorly understood. To assemble this puzzle, several key pieces of information are needed, one in particular being the number of participating B cell...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633029/ https://www.ncbi.nlm.nih.gov/pubmed/23734629 http://dx.doi.org/10.1186/1471-2105-14-S6-S8 |