State of art fusion-finder algorithms are suitable to detect transcription-induced chimeras in normal tissues?

BACKGROUND: RNA-seq has the potential to discover genes created by chromosomal rearrangements. Fusion genes, also known as "chimeras", are formed by the breakage and re-joining of two different chromosomes. It is known that chimeras have been implicated in the development of cancer. Few pu...

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Detalles Bibliográficos
Autores principales: Carrara, Matteo, Beccuti, Marco, Cavallo, Federica, Donatelli, Susanna, Lazzarato, Fulvio, Cordero, Francesca, Calogero, Raffaele A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633050/
https://www.ncbi.nlm.nih.gov/pubmed/23815381
http://dx.doi.org/10.1186/1471-2105-14-S7-S2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633050/
https://www.ncbi.nlm.nih.gov/pubmed/23815381
http://dx.doi.org/10.1186/1471-2105-14-S7-S2

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