Cargando…
State of art fusion-finder algorithms are suitable to detect transcription-induced chimeras in normal tissues?
BACKGROUND: RNA-seq has the potential to discover genes created by chromosomal rearrangements. Fusion genes, also known as "chimeras", are formed by the breakage and re-joining of two different chromosomes. It is known that chimeras have been implicated in the development of cancer. Few pu...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633050/ https://www.ncbi.nlm.nih.gov/pubmed/23815381 http://dx.doi.org/10.1186/1471-2105-14-S7-S2 |