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Identification and analysis of conserved pockets on protein surfaces

BACKGROUND: The interaction between proteins and ligands occurs at pockets that are often lined by conserved amino acids. These pockets can represent the targets for low molecular weight drugs. In order to make the research for new medicines as productive as possible, it is necessary to exploit &quo...

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Detalles Bibliográficos
Autores principales: Cammisa, Marco, Correra, Antonella, Andreotti, Giuseppina, Cubellis, Maria Vittoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633052/
https://www.ncbi.nlm.nih.gov/pubmed/23815589
http://dx.doi.org/10.1186/1471-2105-14-S7-S9