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Search of potential inhibitor against New Delhi metallo-beta-lactamase 1 from a series of antibacterial natural compounds
BACKGROUND: New Delhi metallo-β-lactamase-1 (NDM-1)-producing Gram-negative bacteria are today's major worldwide health concern. The enzyme NDM-1 provides bacterial resistance by its hydrolytic activity against the β-lactam ring of antibiotics. Inhibition of NDM-1 may prevent the hydrolysis of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633303/ https://www.ncbi.nlm.nih.gov/pubmed/23633835 http://dx.doi.org/10.4103/0976-9668.107260 |