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Bevacizumab in high-grade gliomas: a review of its uses, toxicity assessment, and future treatment challenges

High-grade gliomas continue to have dismal prognosis despite advances made in understanding the molecular genetics, signaling pathways, cytoskeletal dynamics, and the role of stem cells in gliomagenesis. Conventional treatment approaches, including surgery, radiotherapy, and cytotoxic chemotherapy,...

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Detalles Bibliográficos
Autores principales: Rahmathulla, Gazanfar, Hovey, Elizabeth J, Hashemi-Sadraei, Neda, Ahluwalia, Manmeet S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633547/
https://www.ncbi.nlm.nih.gov/pubmed/23620671
http://dx.doi.org/10.2147/OTT.S38628