Cargando…

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

Although cell-matrix adhesive interactions are known to regulate stem cell differentiation, the underlying mechanisms, in particular for direct three-dimensional (3D) encapsulation within hydrogels, are poorly understood. Here, we demonstrate that in covalently crosslinked hyaluronic acid (HA) hydro...

Descripción completa

Detalles Bibliográficos
Autores principales: Khetan, Sudhir, Guvendiren, Murat, Legant, Wesley R., Cohen, Daniel M., Chen, Christopher S., Burdick, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633615/
https://www.ncbi.nlm.nih.gov/pubmed/23524375
http://dx.doi.org/10.1038/nmat3586