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Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels
Although cell-matrix adhesive interactions are known to regulate stem cell differentiation, the underlying mechanisms, in particular for direct three-dimensional (3D) encapsulation within hydrogels, are poorly understood. Here, we demonstrate that in covalently crosslinked hyaluronic acid (HA) hydro...
Autores principales: | Khetan, Sudhir, Guvendiren, Murat, Legant, Wesley R., Cohen, Daniel M., Chen, Christopher S., Burdick, Jason A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633615/ https://www.ncbi.nlm.nih.gov/pubmed/23524375 http://dx.doi.org/10.1038/nmat3586 |
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