Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions

Vascular leakage pathologies such as pleural effusion and hemorrhage are hallmarks of anthrax pathogenesis. We previously reported that anthrax lethal toxin (LT), the major virulence factor of anthrax, reduces barrier function in cultured primary human microvascular endothelial cells. Here, we show...

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Detalles Bibliográficos
Autores principales: D’Agnillo, Felice, Williams, Matthew C., Moayeri, Mahtab, Warfel, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633853/
https://www.ncbi.nlm.nih.gov/pubmed/23626836
http://dx.doi.org/10.1371/journal.pone.0062576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633853/
https://www.ncbi.nlm.nih.gov/pubmed/23626836
http://dx.doi.org/10.1371/journal.pone.0062576

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