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Estradiol Represses the G(D3) Synthase Gene ST8SIA1 Expression in Human Breast Cancer Cells by Preventing NFκB Binding to ST8SIA1 Promoter

Recent data have underlined a possible role of G(D3) synthase (GD3S) and complex gangliosides in Estrogen Receptor (ER) negative breast cancer progression. Here, we describe the main transcript of the GD3S coding gene ST8SIA1 expressed in breast tumors. We characterized the corresponding core promot...

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Detalles Bibliográficos
Autores principales: Bobowski, Marie, Vincent, Audrey, Steenackers, Agata, Colomb, Florent, Van Seuningen, Isabelle, Julien, Sylvain, Delannoy, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633854/
https://www.ncbi.nlm.nih.gov/pubmed/23626833
http://dx.doi.org/10.1371/journal.pone.0062559