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A Method to Prioritize Quantitative Traits and Individuals for Sequencing in Family-Based Studies
Owing to recent advances in DNA sequencing, it is now technically feasible to evaluate the contribution of rare variation to complex traits and diseases. However, it is still cost prohibitive to sequence the whole genome (or exome) of all individuals in each study. For quantitative traits, one strat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633859/ https://www.ncbi.nlm.nih.gov/pubmed/23626830 http://dx.doi.org/10.1371/journal.pone.0062545 |