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A Method to Prioritize Quantitative Traits and Individuals for Sequencing in Family-Based Studies

Owing to recent advances in DNA sequencing, it is now technically feasible to evaluate the contribution of rare variation to complex traits and diseases. However, it is still cost prohibitive to sequence the whole genome (or exome) of all individuals in each study. For quantitative traits, one strat...

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Detalles Bibliográficos
Autores principales: Shah, Kaanan P., Douglas, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633859/
https://www.ncbi.nlm.nih.gov/pubmed/23626830
http://dx.doi.org/10.1371/journal.pone.0062545