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Mannose-Binding Lectin Blunts Macrophage Polarization and Ameliorates Lupus Nephritis

BACKGROUND: Deficiency in clearance of self nuclear antigens, including DNA, is the hallmark of systemic lupus erythematosus (SLE), a chronic autoimmnue disease characterized by the production of various autoantibodies, immune complex deposition and severe organ damage. Our previous studies revealed...

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Detalles Bibliográficos
Autores principales: Cai, Yanxing, Zhang, Weijuan, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633861/
https://www.ncbi.nlm.nih.gov/pubmed/23626823
http://dx.doi.org/10.1371/journal.pone.0062465