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Induction of Broadly Neutralising HCV Antibodies in Mice by Integration-Deficient Lentiviral Vector-Based Pseudotyped Particles

INTRODUCTION: Integration-deficient lentiviral vectors (IDLVs) are a promising platform for immunisation to elicit both humoral immunity and cellular mediated immunity (CMI). Here, we compared the specific immunity in mice immunised via different regimens (homologous and cocktail) with IDLV-based HC...

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Detalles Bibliográficos
Autores principales: Deng, Yao, Guan, Jie, Wen, Bo, Zhu, Na, Chen, Hong, Song, Jindong, Yang, Yang, Wang, Yue, Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633868/
https://www.ncbi.nlm.nih.gov/pubmed/23626846
http://dx.doi.org/10.1371/journal.pone.0062684