Prox1 Directly Interacts with LSD1 and Recruits the LSD1/NuRD Complex to Epigenetically Co-Repress CYP7A1 Transcription

Cholesterol 7α-hydroxylase (CYP7A1) catalyzes the first and rate-limiting step in the classical pathway of bile acids synthesis in liver and is crucial for maintaining lipid homeostasis. Hepatocyte nuclear factor 4α (HNF4α) and α(1)-fetoprotein transcription factor (FTF) are two major transcription...

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Detalles Bibliográficos
Autores principales: Ouyang, Huafang, Qin, Yi, Liu, Yanfeng, Xie, Youhua, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633876/
https://www.ncbi.nlm.nih.gov/pubmed/23626788
http://dx.doi.org/10.1371/journal.pone.0062192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633876/
https://www.ncbi.nlm.nih.gov/pubmed/23626788
http://dx.doi.org/10.1371/journal.pone.0062192

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