HDAC Inhibition Induces Increased Choline Uptake and Elevated Phosphocholine Levels in MCF7 Breast Cancer Cells

Histone deacetylase (HDAC) inhibitors have emerged as effective antineoplastic agents in the clinic. Studies from our lab and others have reported that magnetic resonance spectroscopy (MRS)-detectable phosphocholine (PC) is elevated following SAHA treatment, providing a potential noninvasive biomark...

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Detalles Bibliográficos
Autores principales: Ward, Christopher S., Eriksson, Pia, Izquierdo-Garcia, Jose L., Brandes, Alissa H., Ronen, Sabrina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633900/
https://www.ncbi.nlm.nih.gov/pubmed/23626839
http://dx.doi.org/10.1371/journal.pone.0062610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633900/
https://www.ncbi.nlm.nih.gov/pubmed/23626839
http://dx.doi.org/10.1371/journal.pone.0062610

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