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HDAC Inhibition Induces Increased Choline Uptake and Elevated Phosphocholine Levels in MCF7 Breast Cancer Cells
Histone deacetylase (HDAC) inhibitors have emerged as effective antineoplastic agents in the clinic. Studies from our lab and others have reported that magnetic resonance spectroscopy (MRS)-detectable phosphocholine (PC) is elevated following SAHA treatment, providing a potential noninvasive biomark...
Autores principales: | Ward, Christopher S., Eriksson, Pia, Izquierdo-Garcia, Jose L., Brandes, Alissa H., Ronen, Sabrina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633900/ https://www.ncbi.nlm.nih.gov/pubmed/23626839 http://dx.doi.org/10.1371/journal.pone.0062610 |
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