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Crystal Structures of a Plant Trypsin Inhibitor from Enterolobium contortisiliquum (EcTI) and of Its Complex with Bovine Trypsin

A serine protease inhibitor from Enterolobium contortisiliquum (EcTI) belongs to the Kunitz family of plant inhibitors, common in plant seeds. It was shown that EcTI inhibits the invasion of gastric cancer cells through alterations in integrin-dependent cell signaling pathway. We determined high-res...

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Detalles Bibliográficos
Autores principales: Zhou, Dongwen, Lobo, Yara A., Batista, Isabel F. C., Marques-Porto, Rafael, Gustchina, Alla, Oliva, Maria L. V., Wlodawer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633903/
https://www.ncbi.nlm.nih.gov/pubmed/23626794
http://dx.doi.org/10.1371/journal.pone.0062252