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Crystal Structures of a Plant Trypsin Inhibitor from Enterolobium contortisiliquum (EcTI) and of Its Complex with Bovine Trypsin
A serine protease inhibitor from Enterolobium contortisiliquum (EcTI) belongs to the Kunitz family of plant inhibitors, common in plant seeds. It was shown that EcTI inhibits the invasion of gastric cancer cells through alterations in integrin-dependent cell signaling pathway. We determined high-res...
Autores principales: | Zhou, Dongwen, Lobo, Yara A., Batista, Isabel F. C., Marques-Porto, Rafael, Gustchina, Alla, Oliva, Maria L. V., Wlodawer, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633903/ https://www.ncbi.nlm.nih.gov/pubmed/23626794 http://dx.doi.org/10.1371/journal.pone.0062252 |
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