TOM40 Mediates Mitochondrial Dysfunction Induced by α-Synuclein Accumulation in Parkinson’s Disease

Alpha-synuclein (α-Syn) accumulation/aggregation and mitochondrial dysfunction play prominent roles in the pathology of Parkinson’s disease. We have previously shown that postmortem human dopaminergic neurons from PD brains accumulate high levels of mitochondrial DNA (mtDNA) deletions. We now addres...

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Detalles Bibliográficos
Autores principales: Bender, Andreas, Desplats, Paula, Spencer, Brian, Rockenstein, Edward, Adame, Anthony, Elstner, Matthias, Laub, Christoph, Mueller, Sarina, Koob, Andrew O., Mante, Michael, Pham, Emily, Klopstock, Thomas, Masliah, Eliezer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633917/
https://www.ncbi.nlm.nih.gov/pubmed/23626796
http://dx.doi.org/10.1371/journal.pone.0062277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633917/
https://www.ncbi.nlm.nih.gov/pubmed/23626796
http://dx.doi.org/10.1371/journal.pone.0062277

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