Caspase-1 activity affects AIM2 speck formation/stability through a negative feedback loop

The inflammasome is an innate immune signaling platform leading to caspase-1 activation, maturation of pro-inflammatory cytokines and cell death. Recognition of DNA within the host cytosol induces the formation of a large complex composed of the AIM2 receptor, the ASC adaptor and the caspase-1 effec...

Descripción completa

Detalles Bibliográficos
Autores principales: Juruj, C., Lelogeais, V., Pierini, R., Perret, M., Py, B. F., Jamilloux, Y., Broz, P., Ader, F., Faure, M., Henry, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633939/
https://www.ncbi.nlm.nih.gov/pubmed/23630667
http://dx.doi.org/10.3389/fcimb.2013.00014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633939/
https://www.ncbi.nlm.nih.gov/pubmed/23630667
http://dx.doi.org/10.3389/fcimb.2013.00014

Ejemplares similares