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Caspase-1 activity affects AIM2 speck formation/stability through a negative feedback loop

The inflammasome is an innate immune signaling platform leading to caspase-1 activation, maturation of pro-inflammatory cytokines and cell death. Recognition of DNA within the host cytosol induces the formation of a large complex composed of the AIM2 receptor, the ASC adaptor and the caspase-1 effec...

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Detalles Bibliográficos
Autores principales:	Juruj, C., Lelogeais, V., Pierini, R., Perret, M., Py, B. F., Jamilloux, Y., Broz, P., Ader, F., Faure, M., Henry, T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633939/ https://www.ncbi.nlm.nih.gov/pubmed/23630667 http://dx.doi.org/10.3389/fcimb.2013.00014

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