Synergistic Effect of CTLA-4 Blockade and Cancer Chemotherapy in the Induction of Anti-Tumor Immunity

Several chemotherapeutics exert immunomodulatory effects. One of these is the nucleoside analogue gemcitabine, which is widely used in patients with lung cancer, ovarian cancer, breast cancer, mesothelioma and several other types of cancer, but with limited efficacy. We hypothesized that the immunop...

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Detalles Bibliográficos
Autores principales: Lesterhuis, W. Joost, Salmons, Joanne, Nowak, Anna K., Rozali, Esdy N., Khong, Andrea, Dick, Ian M., Harken, Julie A., Robinson, Bruce W., Lake, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633941/
https://www.ncbi.nlm.nih.gov/pubmed/23626745
http://dx.doi.org/10.1371/journal.pone.0061895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633941/
https://www.ncbi.nlm.nih.gov/pubmed/23626745
http://dx.doi.org/10.1371/journal.pone.0061895

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