Proteomic Profiling in Drosophila Reveals Potential Dube3a Regulation of the Actin Cytoskeleton and Neuronal Homeostasis

The molecular defects associated with Angelman syndrome (AS) and 15q duplication autism are directly correlated to expression levels of the E3 ubiquitin ligase protein UBE3A. Here we used Drosophila melanogaster to screen for the targets of this ubiquitin ligase under conditions of both decreased (a...

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Detalles Bibliográficos
Autores principales: Jensen, Laura, Farook, M. Febin, Reiter, Lawrence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633955/
https://www.ncbi.nlm.nih.gov/pubmed/23626758
http://dx.doi.org/10.1371/journal.pone.0061952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633955/
https://www.ncbi.nlm.nih.gov/pubmed/23626758
http://dx.doi.org/10.1371/journal.pone.0061952

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