Penetrating Cations Enhance Uncoupling Activity of Anionic Protonophores in Mitochondria

Protonophorous uncouplers causing a partial decrease in mitochondrial membrane potential are promising candidates for therapeutic applications. Here we showed that hydrophobic penetrating cations specifically targeted to mitochondria in a membrane potential-driven fashion increased proton-translocat...

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Detalles Bibliográficos
Autores principales: Antonenko, Yuri N., Khailova, Ljudmila S., Knorre, Dmitry A., Markova, Olga V., Rokitskaya, Tatyana I., Ilyasova, Tatyana M., Severina, Inna I., Kotova, Elena A., Karavaeva, Yulia E., Prikhodko, Anastasia S., Severin, Fedor F., Skulachev, Vladimir P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633956/
https://www.ncbi.nlm.nih.gov/pubmed/23626747
http://dx.doi.org/10.1371/journal.pone.0061902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633956/
https://www.ncbi.nlm.nih.gov/pubmed/23626747
http://dx.doi.org/10.1371/journal.pone.0061902

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