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Identification of Metabolic Engineering Targets through Analysis of Optimal and Sub-Optimal Routes

Identification of optimal genetic manipulation strategies for redirecting substrate uptake towards a desired product is a challenging task owing to the complexity of metabolic networks, esp. in terms of large number of routes leading to the desired product. Algorithms that can exploit the whole rang...

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Detalles Bibliográficos
Autores principales: Soons, Zita I. T. A., Ferreira, Eugénio C., Patil, Kiran R., Rocha, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633962/
https://www.ncbi.nlm.nih.gov/pubmed/23626708
http://dx.doi.org/10.1371/journal.pone.0061648