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Identification of Metabolic Engineering Targets through Analysis of Optimal and Sub-Optimal Routes
Identification of optimal genetic manipulation strategies for redirecting substrate uptake towards a desired product is a challenging task owing to the complexity of metabolic networks, esp. in terms of large number of routes leading to the desired product. Algorithms that can exploit the whole rang...
Autores principales: | Soons, Zita I. T. A., Ferreira, Eugénio C., Patil, Kiran R., Rocha, Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633962/ https://www.ncbi.nlm.nih.gov/pubmed/23626708 http://dx.doi.org/10.1371/journal.pone.0061648 |
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