Role of Tachykinin 1 and 4 Gene-Derived Neuropeptides and the Neurokinin 1 Receptor in Adjuvant-Induced Chronic Arthritis of the Mouse

OBJECTIVE: Substance P, encoded by the Tac1 gene, is involved in neurogenic inflammation and hyperalgesia via neurokinin 1 (NK1) receptor activation. Its non-neuronal counterpart, hemokinin-1, which is derived from the Tac4 gene, is also a potent NK1 agonist. Although hemokinin-1 has been described...

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Detalles Bibliográficos
Autores principales: Borbély, Éva, Hajna, Zsófia, Sándor, Katalin, Kereskai, László, Tóth, István, Pintér, Erika, Nagy, Péter, Szolcsányi, János, Quinn, John, Zimmer, Andreas, Stewart, James, Paige, Christopher, Berger, Alexandra, Helyes, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634005/
https://www.ncbi.nlm.nih.gov/pubmed/23626716
http://dx.doi.org/10.1371/journal.pone.0061684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634005/
https://www.ncbi.nlm.nih.gov/pubmed/23626716
http://dx.doi.org/10.1371/journal.pone.0061684

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