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Mapping of MN1 Sequences Necessary for Myeloid Transformation

The MN1 oncogene is deregulated in human acute myeloid leukemia and its overexpression induces proliferation and represses myeloid differentiation of primitive human and mouse hematopoietic cells, leading to myeloid leukemia in mouse models. To delineate the sequences within MN1 necessary for MN1-in...

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Detalles Bibliográficos
Autores principales: Kandilci, Ayten, Surtel, Jacqueline, Janke, Laura, Neale, Geoffrey, Terranova, Sabrina, Grosveld, Gerard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634013/
https://www.ncbi.nlm.nih.gov/pubmed/23626719
http://dx.doi.org/10.1371/journal.pone.0061706