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Mapping of MN1 Sequences Necessary for Myeloid Transformation
The MN1 oncogene is deregulated in human acute myeloid leukemia and its overexpression induces proliferation and represses myeloid differentiation of primitive human and mouse hematopoietic cells, leading to myeloid leukemia in mouse models. To delineate the sequences within MN1 necessary for MN1-in...
Autores principales: | Kandilci, Ayten, Surtel, Jacqueline, Janke, Laura, Neale, Geoffrey, Terranova, Sabrina, Grosveld, Gerard C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634013/ https://www.ncbi.nlm.nih.gov/pubmed/23626719 http://dx.doi.org/10.1371/journal.pone.0061706 |
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