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The Calmodulin-Binding, Short Linear Motif, NSCaTE Is Conserved in L-Type Channel Ancestors of Vertebrate Cav1.2 and Cav1.3 Channels

NSCaTE is a short linear motif of (xWxxx(I or L)xxxx), composed of residues with a high helix-forming propensity within a mostly disordered N-terminus that is conserved in L-type calcium channels from protostome invertebrates to humans. NSCaTE is an optional, lower affinity and calcium-sensitive bin...

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Detalles Bibliográficos
Autores principales: Taiakina, Valentina, Boone, Adrienne N., Fux, Julia, Senatore, Adriano, Weber-Adrian, Danielle, Guillemette, J. Guy, Spafford, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634016/
https://www.ncbi.nlm.nih.gov/pubmed/23626724
http://dx.doi.org/10.1371/journal.pone.0061765