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Targeting of PBP1 by β-lactams Determines recA/SOS Response Activation in Heterogeneous MRSA Clinical Strains

The SOS response, a conserved regulatory network in bacteria that is induced in response to DNA damage, has been shown to be associated with the emergence of resistance to antibiotics. Previously, we demonstrated that heterogeneous (HeR) MRSA strains, when exposed to sub-inhibitory concentrations of...

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Detalles Bibliográficos
Autores principales: Plata, Konrad B., Riosa, Sarah, Singh, Christopher R., Rosato, Roberto R., Rosato, Adriana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634065/
https://www.ncbi.nlm.nih.gov/pubmed/23637786
http://dx.doi.org/10.1371/journal.pone.0061083